Research Assistant I

Job Summary:

In the Department of Molecular and Cellular Biology at Harvard University, we research and teach how the collective behavior of molecules and cells forms the basis of life. We are driven by a passion for discovery and value collaborative approaches to scientific inquiry, where connections between people fuel interdisciplinary science and break boundaries across varied experimental systems. Against a backdrop of cutting-edge biological research, we work as a team of educators and mentors to inspire and train the next generation of scientists and global citizens. The Prigozhin Lab at Harvard University develops new biophysical methods for multicolor and dynamic biological imaging at the molecular scale. Our work focuses on capturing cellular dynamics by cryo-vitrifying samples after defined time delays following stimulation, using custom cryo-plunging and high-pressure freezing instruments. In parallel, we are working to achieve multicolor electron imaging via cathodoluminescence—electron-beam–induced optical emission. We apply these methods to study G-protein–coupled receptor signaling, visualize biomolecular condensate formation, and map complex multicellular assemblies such as bacterial biofilms, organoids, and tissues.

Job-Specific Responsibilities:

We invite applications for a full-time Research Assistant I position. The successful candidate will provide comprehensive technical support and conduct experimental work for projects aimed at developing and applying high-resolution biological imaging methods. The position offers an opportunity to gain broad experience at the interface of cell biology, chemistry, and engineering, and the Research Assistant will perform experiments with increasing independence under the guidance and mentorship of the principal investigator and senior lab members. Responsibilities will span several areas depending on the candidate’s background and interests. 

• In cell and molecular biology, the Research Assistant may perform mammalian cell culture and maintenance, transfections or viral transductions, and plasmid design, cloning, and preparation.
• In instrument prototyping and fabrication, the role may involve CAD design; 3D printing and laser cutting; CNC and manual machining; and the assembly and testing of custom instrumentation components.
• In imaging and microscopy, the Research Assistant may contribute to electron microscopy experiments, including cryo-EM, cryo-focused ion beam milling, and room-temperature TEM/SEM, as well as light-microscopy experiments using widefield and confocal fluorescence and super-resolution techniques such as STED and single-molecule localization microscopy.
• The Research Assistant may also gain experience in optics and computation, including optical design and alignment, numerical modeling and simulation using software such as COMSOL or Lumerical FDTD, instrument control and automation using LabVIEW, as well as data and image analysis. 
• The position also includes general laboratory support, such as preparing reagents and solutions, organizing and maintaining equipment and supplies, and documenting protocols and experimental results.

Working Conditions:

• This position is fully on-site; hybrid or remote work is not available, and the successful candidate must be able to work in person in Cambridge, MA. 

Qualifications

Basic Qualifications:

• A B.A./B.S. degree in any area of science, engineering, or a related field is required. 

Additional Qualifications and Skills:

• At least one year of prior laboratory research experience, which may include undergraduate research, is strongly preferred. 
• Basic knowledge of general laboratory practices and procedures. 
• Proficiency with basic computer tools, including the Windows operating system and the Google Drive suite, is required.
• Strong interpersonal skills and the ability to work effectively both independently and as part of an interdisciplinary team.
• Well-organized, with strong attention to detail in both experimental work and written documentation.
• Highly-motivated with excellent time-management, organizational, communication, and problem-solving skills.
• Prior experience with prototyping or fabrication (for example, CAD, 3D printing, or machining) is desirable but not required.
• Familiarity with MATLAB and/or Python is preferred. 

Additional Information

• This is a one-year term position with the possibility of extension contingent on performance and funding.
• Standard Hours: 35 hours per week
• Visa Sponsorship Information: Harvard University is unable to provide visa sponsorship for this position
• Pre-Employment Screening: Identity, Education

Other Information:

• To be considered, applicants must submit a cover letter, and a resume or CV. In the cover letter, candidates are encouraged to briefly describe their research experience and their interest in the Prigozhin Lab.
• Selected Applicants should be prepared to submit three reference letters.
• All formal written offers will be made by FAS HR.

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Work Format Details

This position has been determined by school or unit leaders that all duties and responsibilities must be performed at a Harvard or Harvard-designated location. Certain visa types may limit work location. Individuals must meet work location sponsorship requirements prior to employment.

Salary Grade and Ranges

This position is salary grade level 052. Please visit  Harvard's Salary Ranges  to view the corresponding salary range and related information. 

Benefits

Harvard offers a comprehensive benefits package that is designed to support a healthy work-life balance and your physical, mental and financial wellbeing. Because here, you are what matters. Our benefits include, but are not limited to: 

• Generous paid time off including parental leave 
• Medical, dental, and vision health insurance coverage starting on day one 
• Retirement plans with university contributions 
• Wellbeing and mental health resources 
• Support for families and caregivers 
• Professional development opportunities including tuition assistance and reimbursement 
• Commuter benefits, discounts and campus perks 

Learn more about these and additional benefits on our Benefits & Wellbeing Page. 

EEO/Non-Discrimination Commitment Statement

Harvard University is committed to equal opportunity and non-discrimination. We seek talent from all parts of society and the world, and we strive to ensure everyone at Harvard thrives. Our differences help our community advance Harvard's academic purposes.

Harvard has an equal employment opportunity policy that outlines our commitment to prohibiting discrimination on the basis of race, ethnicity, color, national origin, sex, sexual orientation, gender identity, veteran status, religion, disability, or any other characteristic protected by law or identified in the university's non-discrimination policy. Harvard's equal employment opportunity policy and non-discrimination policy help all community members participate fully in work and campus life free from harassment and discrimination.